Fermalac

General characteristic: 
Main physic-chemical properties:  transparent yellowish gelatin capsules with fine white powder;

Composition:  2 billion freeze-dried organisms per capsule: including Lactobacillus rtiamnosus Rosell-11 (1.6x 10⁹), Yogurt Culture : Streptococcus thermophilus  (0.2 x 10⁹)  and Lactobacillus delbrueckii  subsp. Bulgaricus (0.2 x 10⁹); additional substances.

Form of production.  Vaginal capsules.

Immune and biological properties. Normal vaginal flora consists of lactic acid bacteria that keep pathogenic bacteria under control. Maintaining this normal equilibrium is key to preventing vaginal infections. When infections occur, Fermalac® vaginal aids in restoring the vaginal flora by reintroducing lactic acid bacteria directly in the vaginal environment.

Effect of the preparation is determined by combination of two active ingredients:
Yogurt culture, which consists of Lactobacillus bulgaricus and Streptococcus thermophilus

• balances vagina рН up to 5, and thus keeps pathogenic microorganisms under control;
• produces Н2О2, which inhibits  anaerobic bacteria, patogens of bacterial vaginosis;
• produces folic acid, required for growth of lactobacilli in vagina.

Lactobacillus rhamnosus 

• has a unique ability to keep pathogenic bacteria under control, which provides optimal conditions for restoration of own normal vaginal microflora, local immunity.

Restoration and maintenance of normal vaginal microflora, required when general and local immunity weakening, during treatment with antibiotics, glucocorticoid hormones, cytostatics and immunosuppressants, and also during infectious and inflammatory diseases of reproductive organs, bacterial vaginosis.

Fermalac^® vaginal can be used alone or in conjunction with other gynaecological treatments, as needed.

Indications.

1. Restoration and maintenance of normal vaginal microflora.
2. For prevention and treatment of infectious and inflammatory diseases of reproductive organs (i.e. clamidiosis  and mycoplasmal infection) concurrently with complex gynaecological therapies.
3. Prevention of vulvovaginal candidosis and vaginal dysbcteriosis during treatment with antibiotics.
4. Prevention and treatment of relapse of bacterial vaginosis concurrently with complex therapies with antianaerobic and antibacterial preparations.
5. Prevention of vaginal and urinary bladder inflammatory disease after frequent change of sexual partners.
6. Persistent disorder in vaginal purity 3-4 degree.
7. Non-specific bacterial colpitis, including those provoked by staphylococcus, Escherichia coli or their association.
8. Vaginal inflammatory diseases, connected with deficit of female hormones (after surgery on ovary, age-related low level of estrogens). Can be used alone or in conjunction with complex therapy with estrogenic preparations.
9. Preoperative preparation for vaginal surgery, prevention of infectious-inflammatory complications.
10. Preparation of labor channels for delivery and prevention of infectious-inflammatory diseases in newly born.

Directions & dosage: At bedtime, in a reclining position, insert one capsule deep into the vagina using the applicator. After usage wash the applicator.
Use one capsule per day for 10 consecutive days or as advised by your healthcare practitioner.

Side effect:  Not determined

Contraindications:  Not determined

Warning: Consult physician if vaginal infection and/or symptoms persist beyond the full course of treatment. As with all pharmaceutical products, dis¬continue use and consult physician if symptoms such as nausea or vomiting, bloating, diarrhea or consti¬pation, fluid retention, itching, skin rashes or any other unexplained reactions develop while taking Fermalac® vaginal. A product monograph is available to healthcare practitioners upon request.

Interaction with other pharmaceuticals.  Not determined.  Fermalac® vaginal can be used alone or in conjunction with other gynaecological treatments, as needed.

Overdosage.  Impossible

Storage: Keep refrigerated at not more than + 4о С.

Shelf life. 2 years after date of production.

Sale conditions. No prescription is needed.

Packaging. 10 capsules in plastic bottle with applicator.

Manufacturer. Institute Rosell Inc., Canada.  8480, boul. St-Laurent, Montreal, Canada, H2P 2M6